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Metronidazole vs mebendazole at various doses, the combination is still effective against many common strains of cheap drugstore waterproof eyeliner the bacteria, and authors speculate that the combination offers better long-term results. The main limitations of this study relate to its retrospective evaluation of the treatments – authors report that it is impossible to determine whether there is a direct cause and effect relationship between the antibiotics given and development of cancer. Further, there is a high risk of bias self-reporting due to reporting bias, where people may feel pressured to use antibiotics when sick, and may exaggerate the severity of symptoms to a high degree. This is an important limitation that has been addressed with other studies, like this one. Still, the authors acknowledge that there are limitations in this study. For example, the results may be biased Metacam bestellen ohne rezept if the participants had been ill for much longer after taking the antibiotics than usual – in this study, there was no way to know the severity of illness before taking the antibiotic. authors acknowledge that because there was no way to determine the severity of illness in this study, it might be possible to draw conclusions based on this observation alone. Also, not all participants taking these treatments were diagnosed with the bacteria, and we can't know whether all of the treated patients would or not have developed these diseases in the future. It is possible that some of them would not have ever developed a problem in the first place had they not taken the antibiotic. Another limitation is fact that it not clear how many cases of these infections we would have had if the antibiotics that were not effective had been given at all. But this could be considered a small consideration given that the treatment is so effective. So, it important to keep in mind these limitations evaluating the results of this study as a whole. The main strength of this study is that patients were evaluated before their symptoms worsened and a complete detailed blood analysis was carried out to assess the severity of disease development. authors noted that since the disease does not progress in one direction only but rather evolves on a spiral path, it is very difficult to predict the exact course of disease development before any treatment is started. So, even if the treatment was unsuccessful, doctors should treat in a way that is similar to the course they would have followed had this course progressed, and is what they have recommended by performing the blood analyses in advance and informing their doctors before prescribing the new antibiotic to patients. It is worth noting that the majority (81%) of cancer patients treated with antibiotics who suffered from the development of symptoms bacteria had developed colorectal cancer and that this was the reason why they were prescribed this type of treatment. So, whether or not taking this type of antibiotic will help in preventing other types of cancer in the future cannot be guaranteed. But there are reasons for cautious optimism: First, the results were seen after period of use had expired and the infection was cleared with subsequent treatment other antibiotics. Second, the study population was relatively small – only a few thousand patients. The most important thing to look out for is that the study design very robust – there were no differences between the groups by gender, age, race, duration of illness (or treatment) or the type of tumor in tumors, which indicates that the results were not influenced by selection bias, even while they show a strong correlation between the antibiotic use and development of colon cancer. Finally, despite these limitations, there is reason to believe that this is a strong piece of evidence to support the claim that these antibiotics might help against other types of cancer over and above the effect for primary tumor. Dr Michael Goulson, Reader in Biomedical Ethics, King's College London This article was originally published on The Conversation. Read original article.